virtualenv is a tool for creating isolated virtual python environments. Prior to 21.7.12, download_wheel() accepts pip and setuptools seed wheels fetched for periodic updates or the --download option without checking their bytes against an authoritative digest equivalent to the embedded wheels' BUNDLE_SHA256 verification. A compromised index, stale mirror, or intercepted TLS connection can substitute a different wheel under the requested distribution, version, and filename, after which virtualenv caches and seeds the attacker-controlled wheel into subsequently created environments. The verification applies to the default PyPI path and is intentionally skipped when PIP_INDEX_URL, PIP_EXTRA_INDEX_URL, or PIP_INDEX configures a custom index that may legitimately publish rebuilt wheels. This issue is fixed in version 21.7.12.